UBE2L6 monoclonal antibody, clone k1H3
产品名称： UBE2L6 monoclonal antibody, clone k1H3
英文名称： UBE2L6 monoclonal antibody, clone k1H3
产品编号： MAB2049
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant UBE2L6.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-152 of human UBE2L6.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2b, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12.
Ardley HC, Rose SA, Tan N, Leek JP, Markham AF, Robinson PA.Cytogenet Cell Genet. 2000;89(1-2):137-40.
- 2.
- The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1.
Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA.J Biol Chem. 1999 Oct 22;274(43):30963-8.
- 3.
- Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity.
Kumar S, Kao WH, Howley PM.J Biol Chem. 1997 May 23;272(21):13548-54.
- Entrez GeneID:
- 9246
- Protein Accession#:
- NP_004214
- Gene Name:
- UBE2L6
- Gene Alias:
- MGC40331,RIG-B,UBCH8
- Gene Description:
- ubiquitin-conjugating enzyme E2L 6
- Omim ID:
- 603890
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- retinoic acid induced gene B protein,ubiquitin carrier protein,ubiquitin-protein ligase
- Gene Pathway