MMP9 monoclonal antibody, clone 2C3
产品名称： MMP9 monoclonal antibody, clone 2C3
英文名称： MMP9 monoclonal antibody, clone 2C3
产品编号： MAB1952
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of MMP9.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human MMP9.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western blot (1 to 2 ug/mL)
Immunohistochemistry on formalin to fixed/paraffin to embedded tissues (1 to 5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Circulating MMP2 and MMP9 in breast cancer -- potential role in classification of patients into low risk, high risk, benign disease and breast cancer categories.
Somiari SB, Somiari RI, Heckman CM, Olsen CH, Jordan RM, Russell SJ, Shriver CD.Int J Cancer. 2006 Sep 15;119(6):1403-11.
- 2.
- Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration.
Wang L, Zhang ZG, Zhang RL, Gregg SR, Hozeska-Solgot A, LeTourneau Y, Wang Y, Chopp M.J Neurosci. 2006 May 31;26(22):5996-6003.
- 3.
- Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells.
Chen X, Su Y, Fingleton B, Acuff H, Matrisian LM, Zent R, Pozzi A.Int J Cancer. 2005 Aug 10;116(1):52-61.
- Entrez GeneID:
- 4318
- Gene Name:
- MMP9
- Gene Alias:
- CLG4B,GELB,MMP-9
- Gene Description:
- matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- Omim ID:
- 120361
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq
- Other Designations:
- 92kD type IV collagenase,OTTHUMP00000031674,gelatinase B,macrophage gelatinase,matrix metalloproteinase 9,matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase),matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kD
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenocarcinoma
- Airway Remodeling
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Aneurysm, Dissecting
- Angina Pectoris
- Angina, Unstable
- Aortic Aneurysm
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Arteriosclerosis
- Arthritis, Rheumatoid
- Asthma
- Asthma