周期素D2抗体-抗体-抗体-生物在线
北京索莱宝科技有限公司
周期素D2抗体

周期素D2抗体

商家询价

产品名称: 周期素D2抗体

英文名称: Cyclin D2

产品编号: bs-1148R

产品价格: null

产品产地: 北京

品牌商标:

更新时间: 2025-01-24T10:30:11

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,

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The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.