STK39 (Center) Peptide
产品名称： STK39 (Center) Peptide
英文名称： STK39 (Center) Peptide
产品编号： P2962
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of STK39.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human STK39.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).
Dowd BF, Forbush B.J Biol Chem. 2003 Jul 25;278(30):27347-53. Epub 2003 May 9.
- 2.
- SPAK, a STE20/SPS1-related kinase that activates the p38 pathway.
Johnston AM, Naselli G, Gonez LJ, Martin RM, Harrison LC, DeAizpurua HJ.Oncogene. 2000 Aug 31;19(37):4290-7.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of STK39 polyclonal antibody (Cat # PAB3184) in mouse liver tissue lysate. STK39 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with STK39 polyclonal antibody (Cat # PAB3184) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 27347
- Protein Accession#:
- NP_037365;Q9UEW8
- Gene Name:
- STK39
- Gene Alias:
- DCHT,DKFZp686K05124,PASK,SPAK
- Gene Description:
- serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
- Omim ID:
- 607648
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq
- Other Designations:
- Ste20-like protein kinase,proline-alanine-rich STE20-related kinase,small intestine SPAK-like kinase